I updated the guide.
Removed the Audio Sync=Off nonsense, is should be On if “Estimated Screen Framerate” is properly calibrated.
I added and emphasized the importance of Retroarch being played on the PRIMARY monitor, as in my experience it is the biggest factor in macro stuttering and vsync loss.
I recently purchased few retro consoles (Genesis, Super Famicom) with their flashcarts from krikzz (Mega Everdrive X5 & SD2SNES), to have the real hardware to compare retroarch with.
The most noticeable factors are the feel of the controllers and how smooth the gameplay is.
I view smooth, stutter-free audio/video as a huge part of a good emulation experience.
Having said that, retroarch can give an excellent retro console experience and much more convenient on a CRT when properly set, so much so I choose to play Retroarch with my CRT even though the real consoles are right beneath the TV and also have quality RGB scart cables.