My method was just to change the hotkeys when using DosBox and save it as a core override.
Just “nul” the hotkeys you don’t want, and change the ones you want to keep so they don’t conflict with anything.
I really only play Doom/Wolfenstein so far in DosBox, but here’s what mine ended up looking like for reference:
menu_unified_controls = “false”
input_max_users = “1”
input_hold_fast_forward = “nul”
input_load_state = “nul”
input_save_state = “nul”
input_toggle_fullscreen = “nul”
input_exit_emulator = “p”
input_rewind = “nul”
input_reset = “nul”
input_screenshot = “nul”
input_menu_toggle = “tilde”
(Obviously exit as “P” isn’t ideal, it’s just what I landed on because my use of Xpadder makes my hotkey to quit ESC+P)
Anyway, I hope that makes sense.