All the CORE OPTIONS are stored there. That doesn’t change anything. The multitap configuration is not standard, as in core devs implement that differently. Ekeeke implemented it using controllers in mednafen. In mednafen it’s just a toggle that enables additional ports.
This can be “per-core” if you use a different config yes. But since sometimes it will be a different “controller” as in genplusgx and sometimes it’s a core option that toggles the option it’s not exposed as you would expect.