It could be super handy to be able to execute custom commands by triggering them via hotkeys.
For instance, I often switch between audio output on my laptop speaker and USB headphones. With a Linux CLI command I can do that, but I have to reach out for the keyboard to apply it. With such a feature I could simply hit hotkey+whatever and get the audio to my headset, and hotkey+whateverelse to get it back to the speakers when wife leaves lol.
The possibilities are actually endless. For instance, disable the screen saver timeout, enable/disable the VPN (to get better performances with netplay) and the like.