Yep there is a wild card ^^
Custom Config Per-System you go like my post up there :
<command>D:\Games\EmulationStation\systems\retroarch\retroarch.exe [B]--config D:\Games\EmulationStation\systems\retroarch\configs\customconfig.cfg -L [/B]D:\Games\EmulationStation\systems\retroarch\libretro\fb_alpha_libretro.dll "%ROM%"</command[B]>[/B]
Custom Config Per-Game you go like this :
<command>D:\Games\EmulationStation\systems\retroarch\retroarch.exe [B]--appendconfig[/B][B] D:\Games\EmulationStation\systems\retroarch\configs\[/B][B]%BASENAME%[/B][B].cfg -L [/B]D:\Games\EmulationStation\systems\retroarch\libretro\fb_alpha_libretro.dll "%ROM%"</command[B]>[/B]
Pretty handy for Neo Geo games where you play with a lined-up buttons layout for shooting or puzzle games and switch to square button layout for fighting games. Or when you have a “Retrogaming” category with multiple systems inside 
Works great with fb_alpha_retro.dll. Didn’t try with any other Core.