Starflight for Gensis won't Load after Saving Game

I have this Issue on all the Gensis Core’s.

I use cheats and Save and then when I try to come back to play I just get a Black Screen.

Log from When I load the Game:

[INFO] [CORE]: Using content: E:\Video Games\Sega\Roms\Sega - Mega Drive - Genesis (No-Intro)\Starflight (USA, Europe).zip#Starflight (USA, Europe).md.
[INFO] Content ran for a total of: 00 hours, 00 minutes, 00 seconds.
[INFO] [CORE]: Unloading core..
[INFO] [CORE]: Unloading core symbols..
[INFO] [Video]: Does not have enough samples for monitor refresh rate estimation. Requires to run for at least 4096 frames.
[INFO] RetroArch 1.9.0 (Git 5e551dd92b)
[INFO] [Overrides]: Redirecting save file to "E:\Video Games\RetroArch\RetroArch 1.9.0 (64 Bit)\saves\Starflight (USA, Europe).srm".
[INFO] [Overrides]: Redirecting save state to "E:\Video Games\RetroArch\RetroArch 1.9.0 (64 Bit)\states\Starflight (USA, Europe).state".
[INFO] === Build =======================================
[INFO] CPU Model Name: Intel(R) Core(TM) i5-6500 CPU @ 3.20GHz
[INFO] Capabilities:  MMX MMXEXT SSE SSE2 SSE3 SSSE3 SSE4 SSE4.2 AES AVX
[INFO] Built: Aug  7 2020
[INFO] Version: 1.9.0
[INFO] Git: 5e551dd92b
[INFO] =================================================
[INFO] [CORE]: Loading dynamic libretro core from: "E:\Video Games\RetroArch\RetroArch 1.9.0 (64 Bit)\cores\genesis_plus_gx_libretro.dll"
[INFO] [Overrides]: No core-specific overrides found at E:\Video Games\RetroArch\RetroArch 1.9.0 (64 Bit)\config\Genesis Plus GX\Genesis Plus GX.cfg.
[INFO] [Overrides]: No content-dir-specific overrides found at E:\Video Games\RetroArch\RetroArch 1.9.0 (64 Bit)\config\Genesis Plus GX\Sega - Mega Drive - Genesis (No-Intro).cfg.
[INFO] [Overrides]: No game-specific overrides found at E:\Video Games\RetroArch\RetroArch 1.9.0 (64 Bit)\config\Genesis Plus GX\Starflight (USA, Europe).cfg.
[INFO] [Environ]: GET_CORE_OPTIONS_VERSION.
[INFO] [Environ]: GET_LANGUAGE: "0".
[INFO] [Environ]: RETRO_ENVIRONMENT_SET_CORE_OPTIONS_INTL.
[INFO] [Environ]: SET_CONTROLLER_INFO.
[INFO] [Environ]: SET_INPUT_DESCRIPTORS:
[INFO] Core requested VFS version >= v1, providing v3
[INFO] [Remaps]: remap directory: E:\Video Games\RetroArch\RetroArch 1.9.0 (64 Bit)\config\remaps
[INFO] [Overrides]: Redirecting save file to "E:\Video Games\RetroArch\RetroArch 1.9.0 (64 Bit)\saves\Starflight (USA, Europe).srm".
[INFO] [Overrides]: Redirecting save state to "E:\Video Games\RetroArch\RetroArch 1.9.0 (64 Bit)\states\Starflight (USA, Europe).state".
[INFO] [Environ]: PERFORMANCE_LEVEL: 1.
[INFO] [Environ]: GET_LOG_INTERFACE.
[INFO] [Environ]: PERFORMANCE_LEVEL: 7.
[INFO] [Environ]: SET_SERIALIZATION_QUIRKS.
[INFO] [CONTENT LOAD]: Content loading skipped. Implementation will load it on its own.
[INFO] [Environ]: SET_PIXEL_FORMAT: RGB565.
[libretro INFO] Frontend supports RGB565 - will use that instead of XRGB1555.
[INFO] [Environ]: SYSTEM_DIRECTORY: "E:\Video Games\RetroArch\RetroArch 1.9.0 (64 Bit)\system".
[INFO] [Environ]: GET_SAVE_DIRECTORY.
[libretro INFO] Game Genie ROM should be located at: E:\Video Games\RetroArch\RetroArch 1.9.0 (64 Bit)\system\ggenie.bin
[libretro INFO] Action Replay (Pro) ROM should be located at: E:\Video Games\RetroArch\RetroArch 1.9.0 (64 Bit)\system\areplay.bin
[libretro INFO] Sonic & Knuckles (2 MB) ROM should be located at: E:\Video Games\RetroArch\RetroArch 1.9.0 (64 Bit)\system\sk.bin
[libretro INFO] Sonic & Knuckles UPMEM (256 KB) ROM should be located at: E:\Video Games\RetroArch\RetroArch 1.9.0 (64 Bit)\system\sk2chip.bin
[libretro INFO] Mega Drive TMSS BOOTROM should be located at: E:\Video Games\RetroArch\RetroArch 1.9.0 (64 Bit)\system\bios_MD.bin
[libretro INFO] Game Gear TMSS BOOTROM should be located at: E:\Video Games\RetroArch\RetroArch 1.9.0 (64 Bit)\system\bios.gg
[libretro INFO] Master System (PAL) BOOTROM should be located at: E:\Video Games\RetroArch\RetroArch 1.9.0 (64 Bit)\system\bios_E.sms
[libretro INFO] Master System (NTSC-U) BOOTROM should be located at: E:\Video Games\RetroArch\RetroArch 1.9.0 (64 Bit)\system\bios_U.sms
[libretro INFO] Master System (NTSC-J) BOOTROM should be located at: E:\Video Games\RetroArch\RetroArch 1.9.0 (64 Bit)\system\bios_J.sms
[libretro INFO] Mega CD (PAL) BIOS should be located at: E:\Video Games\RetroArch\RetroArch 1.9.0 (64 Bit)\system\bios_CD_E.bin
[libretro INFO] Sega CD (NTSC-U) BIOS should be located at: E:\Video Games\RetroArch\RetroArch 1.9.0 (64 Bit)\system\bios_CD_U.bin
[libretro INFO] Mega CD (NTSC-J) BIOS should be located at: E:\Video Games\RetroArch\RetroArch 1.9.0 (64 Bit)\system\bios_CD_J.bin
[libretro INFO] Mega CD (PAL) BRAM is located at: E:\Video Games\RetroArch\RetroArch 1.9.0 (64 Bit)\saves\scd_E.brm
[libretro INFO] Sega CD (NTSC-U) BRAM is located at: E:\Video Games\RetroArch\RetroArch 1.9.0 (64 Bit)\saves\scd_U.brm
[libretro INFO] Mega CD (NTSC-J) BRAM is located at: E:\Video Games\RetroArch\RetroArch 1.9.0 (64 Bit)\saves\scd_J.brm
[libretro INFO] Sega/Mega CD RAM CART is located at: E:\Video Games\RetroArch\RetroArch 1.9.0 (64 Bit)\saves\cart.brm
[libretro INFO] INFORMATION - Loading 1048576 bytes ...
[libretro ERROR] Unable to open file.
[INFO] [SRAM]: Skipping SRAM load..
[INFO] Version of libretro API: 1
[INFO] Compiled against API: 1
[INFO] [Cheats]: Load game-specific cheatfile: E:\Video Games\RetroArch\Cheats\cheats (26-3-20)\Genesis Plus GX\Starflight (USA, Europe).cht
[INFO] Applying cheat changes.
[INFO] [Audio]: Set audio input rate to: 44156.86 Hz.
[INFO] [Video]: Video @ 1479x832
[INFO] [GLCore]: Found GL context: wgl
[INFO] [GLCore]: Detecting screen resolution 1920x1080.
[INFO] [WGL] extensions: WGL_ARB_buffer_region WGL_ARB_create_context WGL_ARB_create_context_no_error WGL_ARB_create_context_profile WGL_ARB_create_context_robustness WGL_ARB_context_flush_control WGL_ARB_extensions_string WGL_ARB_make_current_read WGL_ARB_mult
[INFO] [WGL]: Adaptive VSync supported.
[INFO] [WGL]: wglSwapInterval(1)
[INFO] [GLCore]: Vendor: NVIDIA Corporation, Renderer: GeForce GTX 1050/PCIe/SSE2.
[INFO] [GLCore]: Version: 4.6.0 NVIDIA 442.92.
[INFO] [GLCore]: Using resolution 1479x832
[INFO] [Joypad]: Found joypad driver: "dinput".
[INFO] [GLCore]: Loading stock shader.
[INFO] [slang]: Building pass #0 (N/A)
[INFO] [GLCore]: Not using frame history.
[INFO] [GLCore]: Not using framebuffer feedback.
[INFO] [Video]: Found display server: win32
[INFO] [XAudio2]: Requesting 64 ms latency, using 64 ms latency.
[INFO] [Display]: Found display driver: "glcore".
[INFO] [Font]: Using font rendering backend: freetype.
[INFO] [Font]: Using font rendering backend: freetype.
[INFO] [Font]: Using font rendering backend: freetype.
[INFO] [Font]: Using font rendering backend: freetype.
[INFO] [Font]: Using font rendering backend: freetype.
[INFO] [Font]: Using font rendering backend: freetype.
[INFO] [MIDI]: Input disabled.
[INFO] [MIDI]: Output disabled.
[INFO] [MIDI]: Initialized "winmm" driver.
[INFO] Disconnecting device from port 3.
[INFO] Disconnecting device from port 4.
[INFO] Disconnecting device from port 5.
[INFO] Disconnecting device from port 6.
[INFO] Disconnecting device from port 7.
[INFO] Disconnecting device from port 8.
[INFO] Disconnecting device from port 9.
[INFO] Disconnecting device from port 10.
[INFO] Disconnecting device from port 11.
[INFO] Disconnecting device from port 12.
[INFO] Disconnecting device from port 13.
[INFO] Disconnecting device from port 14.
[INFO] Disconnecting device from port 15.
[INFO] Disconnecting device from port 16.
[INFO] [Playlist]: Loading history file: [E:\Video Games\RetroArch\RetroArch 1.9.0 (64 Bit)\content_history.lpl].
[INFO] [Playlist]: Loading history file: [E:\Video Games\RetroArch\RetroArch 1.9.0 (64 Bit)\content_music_history.lpl].
[INFO] [Playlist]: Loading history file: [E:\Video Games\RetroArch\RetroArch 1.9.0 (64 Bit)\content_video_history.lpl].
[INFO] [Playlist]: Loading history file: [E:\Video Games\RetroArch\RetroArch 1.9.0 (64 Bit)\content_image_history.lpl].
[INFO] [Playlist]: Loading favorites file: [E:\Video Games\RetroArch\RetroArch 1.9.0 (64 Bit)\content_favorites.lpl].
[INFO] [GLCore]: VSync => on
[INFO] [WGL]: wglSwapInterval(1)
[INFO] SET_GEOMETRY: 320x224, aspect: 1.306.
[INFO] [GLCore]: VSync => off
[INFO] [WGL]: wglSwapInterval(0)
[INFO] [GLCore]: VSync => on
[INFO] [WGL]: wglSwapInterval(1)
[INFO] Paused.
[INFO] Unpaused.
[INFO] Paused.