Ubuntu Desktop 22.04 fully updated.
When I try to launch either the QT or regular AppImage (tried a few versions including latest stable) as a regular user, I get the below message:
./Applications/RetroArch-Linux-x86_64.AppImage: symbol lookup error: /lib/x86_64-linux-gnu/libEGL_mesa.so.0: undefined symbol: wl_proxy_marshal_flags
If I run as root (sudo), it launches without issue.