I got the same problem. Just fresh install the Retroarch 1.8.1 and i can`t load any Citra core.
[INFO] RetroArch 1.8.1 (Git bfdc8e6a62)
[INFO] === Build =======================================
[INFO] CPU Model Name: AMD Ryzen 7 2700X Eight-Core Processor
[INFO] Capabilities: MMX MMXEXT SSE SSE2 SSE3 SSSE3 SSE4 SSE4.2 AES AVX
[INFO] Built: Nov 2 2019
[INFO] Version: 1.8.1
[INFO] Git: bfdc8e6a62
[INFO] =================================================
[INFO] [Environ]: SET_PIXEL_FORMAT: RGB565.
[INFO] Redirecting save file to "F:\DUCKGAMES\EMULADORES\RetroArch\saves\.srm".
[INFO] Redirecting savestate to "F:\DUCKGAMES\EMULADORES\RetroArch\states\.state".
[INFO] Version of libretro API: 1
[INFO] Compiled against API: 1
[INFO] [Audio]: Set audio input rate to: 30000.00 Hz.
[INFO] [Video]: Video @ fullscreen
[INFO] [GL]: Found GL context: wgl
[INFO] [GL]: Detecting screen resolution 1920x1080.
[INFO] [WGL] extensions: WGL_ARB_buffer_region WGL_ARB_create_context WGL_ARB_create_context_no_error WGL_ARB_create_context_profile WGL_ARB_create_context_robustness WGL_ARB_context_flush_control WGL_ARB_extensions_string WGL_ARB_make_current_read WGL_ARB_mult
[INFO] [WGL]: Adaptive VSync supported.
[INFO] [WGL]: wglSwapInterval(1)
[INFO] [GL]: Vendor: NVIDIA Corporation, Renderer: GeForce GTX 1080 Ti/PCIe/SSE2.
[INFO] [GL]: Version: 4.6.0 NVIDIA 441.20.
[INFO] [GL]: Using resolution 1920x1080
[INFO] [GL]: Default shader backend found: glsl.
[INFO] [Shader driver]: Using GLSL shader backend.
[INFO] [GLSL]: Checking GLSL shader support ...
[WARN] [GL]: Stock GLSL shaders will be used.
[INFO] [GLSL]: Found GLSL vertex shader.
[INFO] [GLSL]: Found GLSL fragment shader.
[INFO] [GLSL]: Linking GLSL program.
[INFO] [GLSL]: Found GLSL vertex shader.
[INFO] [GLSL]: Found GLSL fragment shader.
[INFO] [GLSL]: Linking GLSL program.
[INFO] [GLSL]: Found GLSL vertex shader.
[INFO] [GLSL]: Found GLSL fragment shader.
[INFO] [GLSL]: Linking GLSL program.
[INFO] Setting up menu pipeline shaders for XMB ...
[INFO] [GLSL]: Compiling ribbon shader..
[INFO] [GLSL]: Found GLSL vertex shader.
[INFO] [GLSL]: Found GLSL fragment shader.
[INFO] [GLSL]: Linking GLSL program.
[INFO] [GLSL]: Compiling simple ribbon shader..
[INFO] [GLSL]: Found GLSL vertex shader.
[INFO] [GLSL]: Found GLSL fragment shader.
[INFO] [GLSL]: Linking GLSL program.
[INFO] [GLSL]: Compiling snow shader..
[INFO] [GLSL]: Found GLSL vertex shader.
[INFO] [GLSL]: Found GLSL fragment shader.
[INFO] [GLSL]: Linking GLSL program.
[INFO] [GLSL]: Compiling modern snow shader..
[INFO] [GLSL]: Found GLSL vertex shader.
[INFO] [GLSL]: Found GLSL fragment shader.
[INFO] [GLSL]: Linking GLSL program.
[INFO] [GLSL]: Compiling bokeh shader..
[INFO] [GLSL]: Found GLSL vertex shader.
[INFO] [GLSL]: Found GLSL fragment shader.
[INFO] [GLSL]: Linking GLSL program.
[INFO] [GLSL]: Compiling snowflake shader..
[INFO] [GLSL]: Found GLSL vertex shader.
[INFO] [GLSL]: Found GLSL fragment shader.
[INFO] [GLSL]: Linking GLSL program.
[INFO] [GL]: Using 4 textures.
[INFO] [GL]: Loaded 1 program(s).
[INFO] [GL]: Using GL_RGB565 for texture uploads.
[INFO] [XInput]: Found XInput v1.4.
[INFO] [XInput]: Found controller, user #0
[INFO] [XInput]: Found controller, user #1
[INFO] [XInput]: Pads connected: 2
[INFO] [DINPUT]: Enumerating joypads ...
[INFO] [DINPUT]: Device #0 PID: {0410} VID:{D209}
[WARN] [DINPUT]: Strong rumble unavailable.
[WARN] [DINPUT]: Weak rumble unavailable.
[INFO] [Autoconf]: 143 profiles found.
[INFO] [DINPUT]: Device #1 PID: {0410} VID:{D209}
[WARN] [DINPUT]: Strong rumble unavailable.
[WARN] [DINPUT]: Weak rumble unavailable.
[INFO] [DINPUT]: Device #2 PID: {028E} VID:{045E}
[INFO] [Autoconf]: selected configuration: F:\DUCKGAMES\EMULADORES\RetroArch\autoconfig\xinput\I-PAC Ultimate.cfg
[INFO] [Autoconf]: 143 profiles found.
[INFO] [Autoconf]: selected configuration: F:\DUCKGAMES\EMULADORES\RetroArch\autoconfig\xinput\I-PAC Ultimate.cfg
[INFO] [DINPUT]: Device #3 PID: {028E} VID:{045E}
[INFO] [DINPUT]: Done enumerating joypads ...
[INFO] [XInput]: Attempting autoconf for "I-PAC Ultimate", user #0
[INFO] [XInput]: Attempting autoconf for "I-PAC Ultimate", user #1
[INFO] [XInput]: Attempting autoconf for "XInput Controller (User 1)", user #2
[INFO] [DINPUT]: Found XInput pad at index 0 (DINPUT index 2)
[INFO] [XInput]: Found VID/PID (045E/028E) from DINPUT index 2 for "XInput Controller (User 1)", user #2
[INFO] [XInput]: Attempting autoconf for "XInput Controller (User 2)", user #3
[INFO] [DINPUT]: Found XInput pad at index 1 (DINPUT index 3)
[INFO] [XInput]: Found VID/PID (045E/028E) from DINPUT index 3 for "XInput Controller (User 2)", user #3
[INFO] [XInput]: Attempting autoconf for user #4
[INFO] [XInput]: Attempting autoconf for user #5
[INFO] [XInput]: Attempting autoconf for user #6
[INFO] [XInput]: Attempting autoconf for user #7
[INFO] [XInput]: Attempting autoconf for user #8
[INFO] [XInput]: Attempting autoconf for user #9
[INFO] [XInput]: Attempting autoconf for user #10
[INFO] [XInput]: Attempting autoconf for user #11
[INFO] [XInput]: Attempting autoconf for user #12
[INFO] [XInput]: Attempting autoconf for user #13
[INFO] [XInput]: Attempting autoconf for user #14
[INFO] [XInput]: Attempting autoconf for user #15
[INFO] [Joypad]: Found joypad driver: "xinput".
[INFO] [Autoconf]: 143 profiles found.
[INFO] [Font]: Using font rendering backend: freetype.
[INFO] [Video]: Found display server: win32
[INFO] [XAudio2]: Requesting 64 ms latency, using 64 ms latency.
[INFO] [Autoconf]: selected configuration: F:\DUCKGAMES\EMULADORES\RetroArch\autoconfig\xinput\XInput_Controller_User_1.cfg
[INFO] [Autoconf]: 143 profiles found.
[INFO] [Autoconf]: selected configuration: F:\DUCKGAMES\EMULADORES\RetroArch\autoconfig\xinput\XInput_Controller_User_2.cfg
[INFO] [Menu]: Found menu display driver: "gl".
[INFO] [Font]: Using font rendering backend: freetype.
[INFO] [Font]: Using font rendering backend: freetype.
[INFO] [Menu]: Found menu display driver: "gl".
[INFO] [Font]: Using font rendering backend: freetype.
[INFO] [Font]: Using font rendering backend: freetype.
[INFO] [LED]: LED driver = 'null' 0000000000B8AF00
[INFO] [MIDI]: Initializing ...
[INFO] [MIDI]: Input disabled.
[INFO] [MIDI]: Output disabled.
[INFO] [MIDI]: Initialized "winmm" driver.
[INFO] SRAM will not be saved.
[INFO] Loading history file: [F:\DUCKGAMES\EMULADORES\RetroArch\content_history.lpl].
[INFO] Loading history file: [F:\DUCKGAMES\EMULADORES\RetroArch\content_music_history.lpl].
[INFO] Loading history file: [F:\DUCKGAMES\EMULADORES\RetroArch\content_video_history.lpl].
[INFO] Loading history file: [F:\DUCKGAMES\EMULADORES\RetroArch\content_image_history.lpl].
[INFO] Loading favorites file: [F:\DUCKGAMES\EMULADORES\RetroArch\content_favorites.lpl].
[INFO] [GL]: VSync => on
[INFO] [WGL]: wglSwapInterval(1)
[INFO] [GL]: VSync => on
[INFO] [WGL]: wglSwapInterval(1)
[INFO] [Font]: Using font rendering backend: freetype.
[INFO] [Font]: Using font rendering backend: freetype.
[ERROR] Failed to open libretro core: "F:\DUCKGAMES\EMULADORES\RetroArch\cores\citra_libretro.dll"
[ERROR] Error(s): unknown error 127
[ERROR] Failed to open libretro core: "F:\DUCKGAMES\EMULADORES\RetroArch\cores\citra_canary_libretro.dll"
[ERROR] Error(s): unknown error 127
[INFO] [config] Saved new config to "F:\DUCKGAMES\EMULADORES\RetroArch\retroarch.cfg".
[INFO] Content ran for a total of: 00 hours, 00 minutes, 00 seconds.
[INFO] Unloading game..
[INFO] Unloading core..
[INFO] Unloading core symbols..
[INFO] [Video]: Does not have enough samples for monitor refresh rate estimation. Requires to run for at least 4096 frames.
[INFO] [Video]: Does not have enough samples for monitor refresh rate estimation. Requires to run for at least 4096 frames.