Same here. HW core is unusable for me. I have no issues in any other games.
*Edit -
Ok… now it works for me, with Open gl… it doesnt make any sense. But I changed to vulkan under both the game and in the core, then I changed the resolution. After that I changed to open gl and then it did not crash. I have rebooted after and it still is on open gl. Fully playable at 4x internal and 4k downscaled. Maybe you can try this as well? 
Mednafen and PCSX Rearmed cores dont work for me. I have tried running both .bin and .cue files for both of them using opengl and they refuse to actually play the game. and if i manage to get them to launch its just a greenish screen and nothing else. but as far as testing…I tried it using the android version on my galaxy s7 and had no problems there…So im not really sure what the issue is on my pc. Any help would be greatly appreciated!