"Nuked" audio option for Genesis causes issues to Earthwork Jim music?

I noticed that the Nuked core option (which is the more accurate setting for audio) causes some parts of the music in level 1 (mostly it’s intro) to lag. Like the timing is off in some parts. If you are familiar with the music, you can hear it.

The same happens in BlastEM. This emulator doesn’t have any core options but it’s the more accurate core. This also has the same issue in EWJ.

But if i choose the “MAME” option in GenesisPlusGX, the music sounds correct, or at least, it doesn’t have these timing issues.

I wonder if this is how it’s supposed to be? Like, in the real Genesis the music has these timing issues? Can someone else test this?