Hello, I´m install RETROARCH new release (4r18) and MEGA CD games not working. When I selected a game, the emulator show a black screen and return to previous.
I haven’t used Picodrive and I don’t have an Android device to even try it on, but it sounds like you forgot to collect one or more Mega-CD BIOS files, which are needed to run games. Check the RetroArch Manual, it should tell you where to put the files.