Maybe, maybe not :Check the web on how to properly set the panel into 4:4:4 mode.
Edit - just seen the video and your settings - any reason you are using 144hz for video?
its a range or Gamma mismatch - If its gamma, when the video is playing, open the onscreen shader menu, and sroll to gamma in and gamma out. change it to 2.20 or 2.40 in, and 2.20 or 2.40 out. Should fix the issue for you.
Also, once it clears beta (soon’ish), and pretty major update is on its way.