Nope. Nvidia card (with Nvidia driver obviously). The only two unusual things graphic card/driver related I noticed on my system is that the d3d11 and d3d12 drivers stopped working at some point for me while they worked before (if I try to set the gfx driver to either d3d11 or d3d12 it just crashes RA before even loading any content) starting at 1.11.0 though that was a long time ago. Might be related to this issue:
Glcore and Vulkan works well with one caveat regarding Vulkan is that with N64 cores using the parallel RDP it crashes for me. A few other users at least have reported the issue. As mentioned in that thread, might be gfx driver/card related.
In both cases it appears the issue only affect very few users/systems so understandably it’s harder to debug. Not sure if those issues are related to this problem.
If anyone else has Windows 8 installed please let me know in the thread whether you’re able to load the core or not.