I found this:
Not sure if this applies to your exact model but it might.
According to this the TV is capable of around ~400 nits of peak brightness. It’s also very similar in SDR and HDR mode with SDR mode measuring slightly brighter.
So it doesn’t seem like there’s much advantage to using HDR mode over SDR mode. With that said you shouldn’t have any problems running presets with HDR mode set to On except that they might be a bit dim in very bright environments or if you’re far away from the screen.
You might have to adjust the Peak and Paperwhite brightness to avoid clipping.
Sony Megatron Color Video Monitor recommends an HDR600 or brighter display but it would still run on less bright ones. You would have to determine if it’s bright enough for you.
My other presets, though, the HDR Mega Bezel ones, might be a very good candidate for you because they take full advantage of all the brightness the display has to offer but also uses, brightness “cheats/hacks” in order to get the rest of the way there.
I suggest you try.