It should be able to. I’m able to at 4K on a slightly overclocked GeForce GTX 1070. The CPU is more than capable enough.
This is also dependent to a certain extent on the type of cores and games you would like to emulate though. For example 3D hardware accelerated cores may not have as much headroom.
I’m able to run Nintendo Wii, (Using the Smooth-Advance No reflections base preset) and also, PS1, N64 and Dreamcast/Naomi/Atomiswave with ease (with the Smooth-ADV with full reflections).